Where inflammation, aging, and metabolism converge
We focus on four interconnected areas of chronic inflammatory disease — each with substantial unmet need and a shared underlying biology.
Th2 Inflammation
Atopic dermatitis, asthma, eosinophilic esophagitis, and chronic rhinosinusitis share a type 2 inflammatory signature driven by IL-4, IL-13, and epithelial alarmins.
Read moreInflammaging
Aging immune systems accumulate senescent cells and inflammatory mediators, driving frailty, cardiovascular risk, and neurodegeneration.
Read moreFibroinflammation
Fibrotic disease is an inflammatory process. Persistent immune activation drives fibroblast transformation and irreversible tissue scarring.
Read moreMetabolic Disease
Adipose tissue inflammation links obesity, insulin resistance, and fatty liver disease. Targeting it addresses the root of metabolic syndrome.
Read moreWorking in one of these areas?
We collaborate with academic groups and clinical investigators on translational research in inflammatory disease.
Contact our team