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Alcohol-Induced Symptoms

Chornic Sinusisitis (CRS) symptom exacerbation is a well-known side-effect of alcohol consumption; especially red wine, but also liquorbeer  and other alcoholic beverages. The exact cause for the observed effect is not well understood and probably derives from multifactorial causality.

  • Alcohol increases the release of IgE allergic immunoglobulins may exacerbate CRS symptoms
  • Intolerance to yeasts may exacerbate CRS symptoms
  • Intolerance to sulfites present in red wine, beer and other alcoholic beverages may exacerbate CRS symptoms
    • Sulfites are fairly common allergens
    • Sulfites may irritate the nasal mucosa via oxidative stress and lipid oxidation
  • Consumption of alcholol may promote nasal polyp formation leading to further CRS burden
  • COX-1 inhibitors present in alcoholic beverages such as red wine–and if you suffer from Aspirin-induced asthma as well and/or have high cysteinyl leukotriene blood levels–, consumption may exacerbate respiratory symptoms.
  • Alcohol metabolism byproducts such as acetaldehyde may irritate the nasal mucosa leading to stuffiness and mucus.

Completely stopping alcohol consumption is most certainly the best way to avoid CRS symptom exacerbation. However, alcohol consumption is also part of many people’s lifestyle.

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