The immune system consists in a concerted ensemble of cells, chemicals and processes working to protect organs, skin, respiratory passages, digestive tract and other areas from foreign bodies, such as microbes (organisms such as bacteria, fungi, and parasites), viruses, cancer cells, and toxins.

Above and beyond structural and chemical barriers protecting us from infection, immunity comprises two lines of defense:

1) Innate immunity represents the first line of defense to an intruding pathogen. It is an antigen-independent (non-specific) defense mechanism that is used by the host immediately or within hours of encountering an antigen. The innate immune response has no immunologic memory and, therefore, it is unable to recognize or “memorize” the same pathogen should the body be exposed to it in the future.

2) Adaptive immunity, on the other hand, is antigen-dependent and antigen-specific and, therefore, involves a lag time between exposure to the antigen and maximal response. The hallmark of adaptive immunity is the capacity for memory which enables the host to mount a more rapid and efficient immune response upon subsequent exposure to the antigen.

Innate and adaptive immunity are disctinct mechanisms of host defense, yet complementary. Dysfunctions in either system results in patient vulnerability or skewed responses.

Welnx Therapeutics is dedicated addressing such health issues.

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